Association of BMI with Testosterone in Infertile Males among Local Population

Authors

  • Fahmida Khatoon Department of Biochemistry, Dow University of Health Sciences, Karachi, Pakistan.
  • Farhan Essa Abdullah Department of Microbiology and Immunology, Dow University of Health Sciences, Karachi, Pakistan.
  • Atif Mahmood Department of Physiology, Dow University of Health Sciences, Karachi, Pakistan.
  • Mukarram Ali Department of Forensic Medicine, Dow International Medical College, Dow University of Health Sciences, Karachi, Pakistan.
  • Nadeem Alum Department of Biochemistry, Dow University of Health Sciences, Karachi, Pakistan.
  • Nazrul Hasnain Department of Biochemistry, Dow University of Health Sciences, Karachi, Pakistan.

Keywords:

Male Infertility, BMI, Testosterone, Azoospermia, Oligospermia

Abstract

Objective

To ascertain association of raised BMI with Testosterone levels among infertile males.

Methods

A cross sectional study was conducted from April 2010 to March 2011. Sample size was 300 males (147 infertile and 153 healthy fertile control subjects) aged 30 and 60 years, selected from the Jinnah Postgraduate Medical Center (JPMC), Aziz Medical Center and Abbasi Shaheed Hospital, Karachi. All the subjects were grouped to BMI criteria (Ascian  pacific region for WHO). They were selected by purposive sampling after a detailed medical history and physical examination. Semen analysis was done and blood samples were collected for serum Testosterone levels. Data was analyzed via SPSS 16.0 by using Analysis of Variances (ANOVA) and independent t test to compare the means and to observe sensitivity of tests and to evaluate the significant association with in the group.

Results

A significant negative correlation existed between Testosterone and BMI .Raised BMI appear to have an association with male infertility with the reduction in Testosterone levels.

Conclusion

Obesity is confirmed as risk factor for male infertility in local population.

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Published

2012-06-07

How to Cite

Khatoon, F. ., Essa Abdullah, F. ., Mahmood, A. ., Ali, M. ., Alum, N., & Hasnain, N. . (2012). Association of BMI with Testosterone in Infertile Males among Local Population. Journal of the Dow University of Health Sciences (JDUHS), 6(2), 62–65. Retrieved from https://jduhs.com/index.php/jduhs/article/view/1510

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Original Articles