Frequency of Polycystic Ovaries Syndrome in Reproductive Age Women

Authors

  • Shabnam Abbas Dow Institute of Radiology, Dow University of Health Sciences, Ojha Campus, Suparco Road, Karachi, Pakistan
  • Amjad Sattar Dow Institute of Radiology, Dow University of Health Sciences, Ojha Campus, Suparco Road, Karachi, Pakistan
  • Nauman AL-Qamari Dow Institute of Radiology, Dow University of Health Sciences, Ojha Campus, Suparco Road, Karachi, Pakistan

Keywords:

Polycysticovaries, women, past gynecological events

Abstract

Objective: To determine the frequency of polycystic ovarian syndrome (PCOs) amongst the reproductive age women by ultrasound.

Method: This retrospective cross-sectional study was conducted at Dow Institute of Radiology, Dow University of Health Sciences, Ojha campus, Karachi. The study period spanned from May - October, 2017. All women of reproductive age group (18 - 39 years) having complaints of infrequent or prolonged menstrual periods or excess male hormone (androgen) levels resulting in excess facial and body hair (hirsutism), severe acne or male-pattern baldness were included.  A detailed history of past gynecological events along with demographic characteristics was also obtained.

Results: Of total 1500 women, mean age was 28.01 ±5.71 years. PCOs was found positive in 216 (14.4%) women. Multivariable analysis revealed that age (OR 2.88, 95% CI 1.97-4.19), nulliparity (AOR 5.03, 95% CI 2.84-8.91), primiparity (AOR 3.14, 95% CI 1.50-6.57), history of hormonal intake (AOR 1.18, 95% CI 0.72-1.92), and hirsutism (AOR 4.55, 95% CI 2.45-8.46) were significantly more likely while weight gain (OR 0.40, 95% CI 0.25-0.63) was significantly less likely to have PCOs.

Conclusion: The findings of our study have showed higher frequency of PCOs. Furthermore, increased age, nulliparity, primiparity, history of hormonal intake, and hirsutism were found to be significant associated factors.

Downloads

Download data is not yet available.

References

Stein IF, Leventhal ML. Amenorrhea associated with bilateral polycystic ovaries. Am J Obstet Gynecol 1935; 29:181-91

Zawadski JK, Dunaif A. Diagnostic criteria for polycystic ovary syndrome; towards a rational approach. In: Dunaif A, Givens JR, Haseltine FP, Merriam GR, eds. Polycystic Ovary Syndrome. Boston: Blackwell Scientific 1992: 377-84.

Adams J, Polson DW, Franks S. Prevalence of polycystic ovaries in women with anovulation and idiopathic hirsutism. Br Med J 1986; 293:355-9.

Artini PG, Di Berardino OM, Simi G, Papini F, Ruggiero M, Monteleone P, et al. Best methods for identification and treatment of PCOS. Minerva Ginecol 2010; 62:33-48.

Clayton RN, Ogden V, Hodgkinson J. How common are polycystic ovaries in normal women and what is their significance for the fertility of the population? Clin Endocrinol. 1992; 37:127-34.

Farquhar CM, Birdsall M, Manning P, Mitchell J M, France JT. The prevalence of polycystic ovaries on ultrasound scanning in a population of randomly selected women. Aust N Z J Obstet Gynecol 1994; 34:67-72.

Polson DW, Adams J, Wadsworth J. Polycystic ovaries- a common finding in normal women. Lancet 1988; 1:870-2.

Diamanti-Kandarakis E, Kouli C, Tsianateli T. A survey of PCOS in the Greek island of Lesbos: hormonal and metabolic profile. in the Greek island of Lesbos: hormonal and metabolic profile. J Clin Endo Metabol 1999; 84:4006–11.

Yildiz BO, Yarali H, Oguz H, Bayraktar M. Glucose intolerance, insulin resistance, and hyperandrogenemia in first degree relatives of women with polycystic ovary syndrome. J Clin Endocrinol Metab 2003; 88:2031-6.

Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil Steril 2004; 81:19-25.

Kelekci Kh, Kelekci S, Incki K, Ozdemir O, Yilmaz B., Kelekci S, Incki K, Ozdemir O, Yilmaz B. Ovarian morphology and prevalence of polycystic ovary syndrome in reproductive aged women with or without mild acne. Int JDermatol. 2010; 49:775-9.

O, Zini M, Williams S, Ighere J. The prevalence of polycystic ovary morphology among women attending a new teaching hospital in southern Nigeria. Afr J Repord Health 2014; 18:160-3.

Jalilian A, Kiani F, Sayehmiri F, Sayehmiri K, Khodaee Z, Akbari M. Prevalence of polycystic ovary syndrome and its associated complications in Iranian women: A meta-analysis. Iran J Reprod Med 2015; 13:591-604.

Miyoshi A, Nagai S, Takeda M. Ovarian morphology and prevalence of polycystic ovary syndrome in Japanese women with type 1 diabetes mellitus. J Diabetes Investig 2013; 4:326-9.

Orio F, Palomba S, Carbone M, Muscogiuri G. Prevalence of polycystic ovary morphology in a region of South Italy. J Ultrasound 2016; 19:301-2.

Franks S. Polycystic ovary syndrome in adolescents. Int J Obesity 2008; 32:1035–41.

Blank SK, Helm KD, McCartney CR, Marshall JC. Polycyst - ic ovary syndrome in adolescence. Ann N Y Acad Sci 2008; 1135:76–84.

Guraya SS. Prevalence and ultrasound features of polycystic ovaries in young unmarried Saudi females. J Micros Ultrastruct 2013; 1:30-4.

Franks S, Gilling-Smith C, Watson H, Willis D. Insulin action in the normal and polycystic ovary. Endocrinol Metab Clin North Am 1999; 28:361–78.

Takahashi K, Eda Y, Abu-Musa A, Okada S, Yoshino K, Kitao M. Transvaginal ultrasound imaging, histopathology and endocrinopathy in patients with polycystic ovarian syndrome. Hum Repro 1994; 9:123-6.

Fox R, Corrigan E, Thomas PA and Hull MGR The diagnosis of polycystic ovaries in women with oligo-amenorrhoea: predictive power of endocrine tests. Clin Endo 1991; 34:127–31.

Kyei-Mensah AA, Lin Tan S, Zaidi J, Jacobs HS. Relation - ship of ovarian stromal volume to serum androgen concentrations in patients with polycystic ovary syndrome. Hum Repro 1998; 13:1437-41.

Rodin DA, Bano G, Balnd JM, Taylor K, Nussey SS. Polycystic ovaries and associated metabolic abnormalities in Indian subcontinent Asian Women. Clin Endocrinol 2002; 49:91-2.

Rackow BW, Brink HV, Hammers L, Flannery CA, Lujan M- E, Burgert TS. Ovarian Morphology by Transabdominal Ultrasound Correlates With Reproductive and Metabolic Disturbance in Adolescents With PCOS. J Adolesc Health 2018; 62:288-93.

Louwers YV, Lao O, Fauser BC, Kayser M, Laven JS. The impact of self-reported ethnicity versus genetic ancestry on phenotypic characteristics of polycystic ovary syndrome (PCOS). J Clin Endocrinol Metab 2014; 99:E2107-16.

Downloads

Published

2018-08-26

How to Cite

Abbas, S. ., Sattar, A. ., & AL-Qamari, N. . (2018). Frequency of Polycystic Ovaries Syndrome in Reproductive Age Women. Journal of the Dow University of Health Sciences (JDUHS), 12(2), 53–57. Retrieved from https://jduhs.com/index.php/jduhs/article/view/1360

Issue

Section

Original Articles