Perceptions of Health Status, Medication Side effects and Depression after Successful Renal Transplantation

Fatima Kamran, Afsheen Masood


Objective: To investigate the perceptions of health status and depression among Renal Transplant
Recipients (RTRs).
Stydy Design: A longitudinal research design was used.
Methods: Recipients’ perceived health status (PHS) was measured by a self-developed questionnaire
that reflected the symptom severity and frequency of common immunosuppressant side effects.
Depression levels were assessed using Beck Depression Inventory B.D.I II) .The sample population
comprised of RTRs with a successful and healthy renal transplant recruited from private and government
sector renal units in Lahore, Pakistan.
Results: Recipients with poorer perceptions of health status tend to be more depressed as indicated
by significant negative correlations between PHS and depression. However, further regression analysis
found both constructs as significant predictors of each other, raising a question of causal direction. A
cross lagged correlation analysis indicated that PHS appears to be a stronger predictor of depression
comparatively. Most recipients tend to have positive perceptions of their health status (M = 30.84, S.D
= 3.64) with minimum to moderate level of depression (M = 9.50, S.D = 4.00), It is found that a
positive perception of health status is associated with lowered depression.
Conclusion: Most recipients’ with a healthy kidney transplant tend to report a positive perception of
their health status despite adverse medication side effects. However, the perceived health status is
significantly associated with consequent feeling of depression. The study confirms the efficacy and
positive health outcomes of renal transplantation in Pakistan.


Perceived Health Status; Renal Transplant Recipients; Depression; Medication side effects; Transplantation

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