Outcomes of Antibiotics as Primary Therapy in Uncomplicated Acute Appendicitis at PUMHS Nawabshah

Authors

  • Gulshan Ali Memon Department of General Surgery, People’s University of Medical and Health Sciences, Nawabshah, Pakistan
  • Khawar Saeed Jamali Professor of Surgery and Vice Chancellor Dow University of Health Sciences, Karachi.
  • Syed Kashif Ali Shah Department of General Surgery, People’s University of Medical and Health Sciences, Nawabshah, Pakistan
  • Habib Ur Rehman Department of General Surgery, People’s University of Medical and Health Sciences, Nawabshah, Pakistan
  • Shahnawaz Leghari Department of General Surgery, People’s University of Medical and Health Sciences, Nawabshah, Pakistan
  • Shahida Baloch Department of General Surgery, People’s University of Medical and Health Sciences, Nawabshah, Pakistan

Keywords:

Acute appendicitis, Appendectomy, Antibiotic treatment

Abstract

Objective: Over bearing, appendectomies have continuously been pushing the surgical wisdom to connote on non-operative option of treatment so this study was designed with an objective to assess the outcomes of antibiotics as primary therapy for un–complicated acute appendicitis.
Methods: A total of 96 patients of both genders from 16 to 60 years of age having uncomplicated acute appendicitis enrolled in this study were treated with antibiotics and were discharged on third day with having oral treatment on ciprofloxacin (500mg) twice a day and metronidazole (400mg) thrice a day for 07 days. Routine follow up was taken on days 15, 30, 90 180 and 360 and outcomes were recorded.

Results: Among 96 patients, 10 (10.41%) worsened in symptoms (pain on visual analogue scale) were confirmed with WBC & Ultrasound reports and under went for appendectomies during initial hospital stay. While within 9 months, during follow up 11 (11.45%) patients were readmitted in hospital and operated after confirmation on re-examination and re- investigations. Total of 21 (22%) patients were subjected to appendectomy.
Conclusion: Under proper observation, antibiotic treatment can be safe and effective in un-complicated acute appendicitis with reduced recurrence.

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Published

2017-04-29

How to Cite

Memon, G. A., Jamali, K. S., Shah, S. K. A., Rehman, H. U., Leghari, S., & Baloch, S. (2017). Outcomes of Antibiotics as Primary Therapy in Uncomplicated Acute Appendicitis at PUMHS Nawabshah. Journal of the Dow University of Health Sciences (JDUHS), 11(1), 6–10. Retrieved from https://jduhs.com/index.php/jduhs/article/view/1418

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Original Articles