TOXIC EFFECTS OF LEAD ON THE GERMINAL EPITHELIUM IN MALE ALBINO RATS

Authors

  • Muhammad Rafique
  • Farrah Shams
  • Surriyya Sarwat
  • Sadia Qazi

Keywords:

Lead chloride, Albina rats, Seminiferous tubules, Germinal epithelium

Abstract

To determine the toxic effects of lead on the germinal epithelium of testes of albino rat.

Study Design: Experimental study.

Place and Duration of Study: Basic Medical Sciences Institute, Jinnah Postgraduate Medical Center, Karachi, from August 2003 to December 2005.

Method: Forty adult Albino rats selected for the study were divided into two groups; groups A, received injections normal saline 1 ml interaperiotoneally dailyu for eight weeks. Grops B received lead chloride in a dose of 10 mg / kg body wieght intraperitoneally daily.  the testes were removed and fixed in Bouin's fluid for 24 hours. They were dehydrated in ascending strenght of alcohol and the paraffin block were made. From um stick tissue sections were obtained, stained with PAS Irom Hematoxylin method and the morphometric study was done. Student's T-test was used for statistical analysis. 

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Published

2009-06-18

How to Cite

Rafique, M. ., Shams, F., Sarwat, S. ., & Qazi, S. (2009). TOXIC EFFECTS OF LEAD ON THE GERMINAL EPITHELIUM IN MALE ALBINO RATS. Journal of the Dow University of Health Sciences (JDUHS), 3(2), 55–60. Retrieved from https://jduhs.com/index.php/jduhs/article/view/1316

Issue

Vol. 3 No. 2

Section

Original Articles

License

Copyright (c) 2021 Muhammad Rafique, Farrah Shams, Surriyya Sarwat, Sadia Qazi

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Articles published in the Journal of Dow University of Health Sciences are distributed under the terms of the Creative Commons Attribution Non-Commercial License https://creativecommons.org/ licenses/by-nc/4.0/. This license permits use, distribution and reproduction in any medium; provided the original work is properly cited and initial publication in this journal.